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These adjustments at three levels of the AR signaling axis, alone or in combination, allow CaP to progress in an AR-dependent manner under ADT
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Mol Cell Biol 2000;20:1868-76.PubMedPMC 47

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Serious but rare adverse effects include pancreatitis, gallbladder disease, acute kidney injury (usually secondary to dehydration from gastrointestinal symptoms), and hypoglycemia when combined with insulin or sulfonylureas

The table below lists known drug-drug interactions between HCV DAAs and selected medications
